A new study in the
Journal of the American Medical Association reports that teenagers who take antipsychotic medications are at risk of becoming overweight or obese, and for developing metabolic syndrome.
Metabolic syndrome includes symptoms such as overweight, too much abdominal fat, and abnormal cholesterol and high blood pressure. Some of the teenagers who took these medications developed symptoms of cardiovascular disease.
- Dr. Christoph Correll of Zucker Hillside Hospital in New York and his colleagues studied 272 patients ages 4 to 19 years old who were taking drugs such as Abilify, Zyprexa, Seroquel, and Risperdal.
- Between 10 and 36 percent of the studied teens became overweight or obese.
- Dr. Correll recommended that "the cardiometabolic risk of these drugs in children should be balanced through careful assessment of the indication for their use, consideration of lower risk alternative, and proactive adverse effect monitoring and management."
"Cardiometabolic adverse effects, such as age-inappropriate weight gain, obesity, hypertension, and lipid and glucose abnormalities are particularly problematic during development," said Dr. Correll, "because they predict adult obesity, the metabolic syndrome, cardiovascular morbidity, and malignancy."